Diffuse palmoplantar keratoderma is an autosomal dominant condition consisting of an even, smooth plate of hyperkeratotic yellowish skin covering the palms and soles. There is an erythematous border with the normal skin.
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Palmoplantar keratoderma with deafness -- Two GJB2 mutations have been reported in individuals with this condition in which the skin on the palms and soles of the feet is unusually thick.
A few people with oculodentodigital dysplasia also have a skin condition called palmoplantar keratoderma. Palmoplantar keratoderma causes the skin on the palms and the soles of the feet to become thick, scaly, and calloused.
palmoplantar keratodermas (PPK)
peeling skin syndrome
pityriasis rubra pilaris (PRP)
Refsum's disease (phytanic acid storage disease)
Rud's syndrome
Sjogren-Larsson syndrome
Tay's syndrome (trichothiodystrophy, IBIDS syndrome)
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 See also: Symptom, Dysplasia, Autosomal dominant, Keratosis, Cancer
  
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