Primary Lateral Sclerosis |
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NINDS Primary Lateral Sclerosis Information Page
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Juvenile primary lateral sclerosis
Related Gene(s)
References
Quick links to this topic MedlinePlus Health information Additional NIH Resources National Institutes of Health Educational resources Information pages Patient support ...
Primary lateral sclerosis and progressive pseudobulbar palsy
Diagnosis
Treatment ...
- Primary Lateral Sclerosis - Support Group
Spastic Paraplegia Foundation, Inc. - Spastic Paraparesis / Familial Spastic Paraplegia - Support Group
Spastic Spinal Familial Paralysis
Spastic Spinal Monoplegia Syndrome ...
Primary Lateral Sclerosis see Motor Neurone disease
Primary Progressive Aphasia see Frontotemporal Lobar Degeneration including Frontotemporal Dementia
Progressive Bulbar Palsy see Motor Neurone disease ...
Primary lateral sclerosis? Amyotrophic lateral sclerosis?
Does individual have muscle weakness and wasting in the hand, arms, and legs? Does any involuntary muscle twitching (fasciculation) occur?
Superoxide dismutase 1, soluble (SOD1)
Neurofilament, heavy polypeptide (NEFH)
Myotrophic lateral sclerosis 2 (juvenile) (ALS2)
Primary Lateral Sclerosis
Senataxin (SETX) ...
Progressive Bulbar Palsy, Included
Benign Focal Amyotrophy of ALS
Upper Motor Neuron Disease
Werdnig-Hoffman Disease
Wohlfart-Disease
Primary Lateral Sclerosis
Infantile Spinal Muscular Atrophy, ALS
Kugelberg-Welander Disease ...
(also called sporadic) MND are caused by unknown factors, although scientists think environmental toxins or viruses could act as disease triggers. Nonhereditary MND include ALS, progressive bulbar palsy, pseudobulbar palsy, primary lateral sclerosis, ...
Jankovic-Rivera syndrome ... speech defect
Juvenile dermatomyositis ... nasal voice
Juvenile Myasthenia Gravis ... speech problems
Juvenile pilocytic astrocytoma ... speech problems
Juvenile primary lateral sclerosis ... slurred speech ...
Drugs, Agents, Antirheumatic, Opiate Receptors, Oryzaviruses, Zygotes, Plant, P Hydroxyphenylpyruvate Hydroxylase, P68 Protein Kinase, Persons, Institutionalized, Phosphoenolpyruvate Carboxykinase (ATP) CAS RN, Primary Lateral Sclerosis, ...
Primary lateral sclerosis (PLS). This is a rare type of MND. It mainly causes weakness in the leg muscles. Some people with this type may also develop clumsiness in the hands or develop speech problems.
With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089) ...
conveying impulses from the central nervous system to a muscle, gland, or other effector tissue resulting in conditions such as progressive muscular atrophy, amyotrophic lateral sclerosis, progressive bulbar paralysis and primary lateral sclerosis ...
In progressive muscular atrophy and related syndromes the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy, the initial degeneration occurs in the brainstem. In primary lateral sclerosis, ...
 See also: Lateral Sclerosis, Sclerosis, Atrophy, Palsy, Muscular atrophy
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