"Previous work in our lab showed that when these kinase enzymes - Cdk4 or Cdk6 - inappropriately match up with regulatory proteins called cyclin D1 or D2, you get the uncontrolled proliferation of cells that is a hallmark of myeloma relapse, ...
Proliferation - The growth and reproduction of similar cells.
Protein losing enteropathy - The loss of protein in the intestine.
Radiotherapy - The treatment of disease by radiation.
Cell proliferation: An increase in the number of cells as a result of cell growth and cell division.
Cellular adhesion: The close adherence (bonding) to adjoining cell surfaces.
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Lymphoid hyperplasia ...
Proliferation - new blood vessels grow to bring nutrients to your wound and remove dead tissue.
Maturation - new skin seals your wound and forms a scar.
Proliferation of organisms within the phagolysosome eventually ruptures the host cell.
A proliferation of vascular channels filled with red blood cells, shown here beneath skin at the left, is consistent with a hemangioma. If large, such a neoplasm can increase cardiac output, leading to heart failure and hydrops fetalis.
The proliferation of Wi-Fi and high-speed Internet makes it relatively easy for a hospital to offer such videoconferencing to child patients, Hilfer said.
"I hope it catches on," he said.
T-cell proliferation assays to mitogens, antigens, or irradiated allogeneic WBCs
Low percentage of T cells, lymphopenia, suspected SCID or complete DiGeorge syndrome ...
A bony proliferation and articular degeneration of the first METATARSOPHALANGEAL JOINT that is characterized by pain and a progressive decrease in the dorsiflexion range of motion.
Hallux Rigidus ...
With the proliferation of PSA for early detection, reviews of large numbers of asymptomatic men with prostate cancer found that most have organ-confined disease.
When cell proliferation occurs in a controlled and contained manner, the resulting spot is noncancerous (benign) and is commonly referred to as a mole or nevus.
Sweat Duct Proliferation Associated…
Related Articles Sweat duct proliferation associated with aggregates of elastic tissue and… more…
[Atrophodermia Vermiculata] ...
An excessive proliferation of blood vessels that leads to a mass, most frequently noticed on the skin present since birth
Vomiting of blood ...
myointimal proliferation: the multiplying of cells lining the blood vessels
myopericarditis: inflammation and irritation of the heart muscle and the membrane covering the heart
pericardium: membrane covering the heart ...
The adenomatous proliferation is characterized by different degrees of cell dysplasia (atypia or loss of normal differentiation of epithelium) irregular cells with hyperchromatic nuclei, (pseudo)stratified nuclei, nucleolus, decreased mucosecretion, ...
Proliferation The reproduction or multiplication of similar forms, especially of cells and morbid cysts.
Prostate-Gland A gland in men that surrounds the neck of the bladder and urethra.
benign vascular proliferation in dogs; resembles cavernous hemangioma.
varicose veins ...
Proliferation rapid cell division. Promoter DNA sequence to which RNA polymerase binds to initiate transcription. Pro-oxidant an atom or molecule that promotes oxidation of another atom or molecule by accepting electrons.
Significant hyperproliferation of keratinocytes leads to a very thick area of hyperkeratosis. Weight compresses this hyperkeratotic area driving out air, causing the development of a transparent clavus ("corn").
Whether the clonal proliferation of LCH cells is a result of neoplastic changes or immunologic abnormalities, the primary treatment is with chemotherapeutic agents. Some of the chemotherapy drugs used have immunomodulatory activity as well.
: Angiocentric immunoproliferative lesions: a clinicopathologic spectrum of post-thymic T-cell proliferations. Blood 72 (5): 1674-81, 1988.
Liang R, Todd D, Chan TK, et al.: Treatment outcome and prognostic factors for primary nasal lymphoma.
and reproductive tracts produce a form of IgA (IGA, Secretory) that serves to protect these ports of entry into the body Immunoblastic Lymphadenopathy A disease characterized by fever, itching, rash, sweating spells, weight loss, proliferation of ...
Analysis of anti-proliferation of curcumin on human breast cancer cells and its mechanism. 83(20):1764-8.
Sansom, C. (2001). Curry component may be chemopreventive for colon cancer. Lancet Oncol, 2(2);67.
Sun, H. (2008).
Soluble form of amyloid precursor protein regulates proliferation of progenitors in the adult subventricular zone. Development. 2004 May;131(9):2173-81. Epub 2004 Apr 08. PubMed citation
Conti L, Cattaneo E.
Ductal carcinoma in situ (DCIS): A precancerous condition characterized by the clonal proliferation of malignant-looking cells in the lining of a breast duct without evidence of spread outside the duct to other tissues in the breast or outside ...
Gall A localized proliferation of plant or parasite tissue that produces an abnormal growth or swelling, usually caused by pathogenic organisms, nematodes, or insects.
Endometrial hyperplasia is a proliferation (excessive growth) or thickening of the endometrium which may involve part or all of the endometrium.
There is no significant necrosis (cell death) or vascular proliferation (increased blood vessel growth - cancerous tumours create extra blood vessels).
Grade II - slow-growing tumours with more rapidly dividing cells.
to suggest that normalization of esophageal acid exposure decreases cancer risk in these patients, recent studies show that short-term normalization of intraesophageal acid exposure in Barrett's esophagus patients decreases cellular proliferation and ...
The rapid proliferation of abnormal myeloid WBCs and their reduced ability to mature and to die normally results in their accumulation in the bone marrow.
A grade II tumor does not have mitosis, vascular proliferation (blood vessels growing to the tumor), or necrosis (dead cells in the tumor), but shows increased cellularity (an abnormally large number of cells).
Of course, retarding the growth and proliferation of cold sores is not the only trick up lysine's sleeve.
In normal development, neuron proliferation - the process in which nerve cells divide to form new generations of cells - is regulated so that the correct number of cells is produced in the proper place at the appropriate time.
A hematopoietic growth factor which promotes proliferation and maturation of neutrophil granulocytes.
coli (EIEC) is distinguished by the presence of a plasmid containing genes that code for Shiga-like toxin which permits invasion, proliferation and ultimately destruction of epithelial cells.
What is a beryllium lymphocyte proliferation test (BeLPT)?
The beryllium lymphocyte proliferation test (BeLPT) is a test that measures beryllium sensitization, which is the immune system's reaction to beryllium.
These are biological substances that exert their influence by causing cellular growth and proliferation.
Gestational Trophoblastic Disease ( GTD) is a group of disorders that result in the abnormal proliferation of placental (trophoblastic) tissue.
apoptosis ; cancer ; cell ; cell division ; cell proliferation ; chromosome ; dysplasia ; gastrointestinal ; gene ; genitalia ; hepatosplenomegaly ; hernia ; hypertelorism ; incidence ; intestine ; kidney ; macrocephaly ; macroglossia ; macrostomia ; ...
Skin biopsy shows vascular proliferation and infiltration of vessel walls by neutrophils and clumps of organisms seen with Warthin-Starry silver staining.
2. infectious disease characterized by fever and granulomatous cutaneous lesions.
Mutations in genes that control normal cell proliferation can lead to cancer. These mutations can be created by DNA-damaging carcinogens such as cigarette by-products and radiation.
Leukemia is a neoplastic diseases of the bone marrow in which unrestrained proliferation of white blood cells occurs, usually accompanied by anemia, impaired blood clotting, and enlargement of the lymph nodes, liver, and spleen.
Leukemia articles: ...
In this era of pink ribbons and yellow Livestrong bracelets and a proliferation of races to cure cancer, it's easy to forget that just three or four decades ago, a cancer diagnosis was likely a death sentence.
A precancerous condition characterized by the clonal proliferation of malignant-looking cells in the lining of a breast duct without evidence of spread outside the duct to other tissues in the breast or outside the breast.
To identify certain forms of cell proliferation as neoplastic, it is necessary to demonstrate that the cell population is genetically identical to a single progenitor cell (clonality).
When a woman is pregnant, the hormones estrogen, progesterone and prolactin cause proliferation of the lobules and ducts within the breast.
Without essential amino acids, angiogenesis, fibroblast proliferation, collagen synthesis, and scar remodeling will not occur. Amino acids also support the immune response.
Such damage inhibits skin cell proliferation and reduces psoriasis plaque formation. PUVA employs a combination of a psoralen drug and UVA radiation. Forms of psoralen include methoxsalen, 8-methoxypsoralen (8-MOP), or bergapten (5-MOP).
The naevus cells form a row along the dermoepidermal junction (called lentiginous proliferation), with or without naevus cells in nests (called theques).
These theques are often irregular in size and shape and may 'bridge' or join together.
Definition Pinguecula and pterygium are both non-malignant, slow-growing proliferations of conjunctival connective tissue in the eye. Pterygia, but not pingueculae, extend over the cornea.
Eosinophilic esophagitis is inflammation of the esophagus due to an over-proliferation of white blood cells (eosinophils) in the lining of the esophageal wall. This leads to dysmotility of the esophagus and difficulty swallowing.
Most moles are simply the result of a harmless proliferation of the pigment cells within the deeper layer of the skin. A few of these moles, called congenital melanonaevi, are usually present at birth.
A condition characterised by proliferation of cells resembling lymphocytes or plasma cells in the bone marrow, anaemia, increased sedimentation rate and hyperglobulinaemia.
Mutation Identified That Causes Skin Hyperproliferation
Scientists have identified a mutation in a gene that causes patches of very thick skin to appear on the palms and soles of affected people.
Acute glomerulonephritis refers to a specific set of renal diseases in which an immunologic mechanism triggers inflammation and proliferation of glomerular tissue.
A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow.
DID is a disorder characterized by identity fragmentation rather than a proliferation of separate personalities.
Prolactin has been found to stimulate proliferation of oligodendrocyte precursor cells. These cells differentiate into oligodendrocytes, the cells responsible for the formation of myelin coatings on axons in the central nervous system.
Untreated and/or advanced leukemia results in a proliferation of abnormal white blood cells that spread throughout the blood stream. These abnormal cells crowd out normal white blood cells.
Proliferation of the synovium is more limited, and joint destruction is rare. The joints most commonly involved are those of the fingers, wrists, and knees; less commonly involved are the elbows, ankles, and shoulders.
neoplasm - any abnormal growth of new tissue; a proliferation of cells no longer under normal physiologic control. These may be benign (non-cancerous) or malignant (cancerous).
neuropathology - the pathology of the nervous system.
hyperplasia: Overproliferation of normal cells within a normal tissue structure.
hypersomnia: Excessive daytime sleepiness.
hypertension: Persistently high arterial blood pressure.
This thickening is the beginning of intimal proliferation and plaque formation. The distribution, severity (amount of plaque), and rate of growth of the plaques in the coronary arteries vary greatly from person to person.
In polycythemia vera, uncontrolled and rapid cellular reproduction and maturation cause proliferation or hyperplasia of all bone marrow cells (panmyelosis).
Definition Sturge-Weber angiomatosis is developmental condition characterized by proliferation of vascular tissues involving the face and the brain. The condition is non-hereditary in nature and is rarely encountered.
CANCER: a malignant neoplasm or tumor characterized by abnormal cell proliferation.
BeLPT (beryllium lymphocyte proliferation test)-a blood test that determines allergic sensitivity to beryllium
Lung biopsy -to test lung tissue using a bronchoscope (a thin, lighted tube that is inserted into the airways) to remove the sample ...
multiple myeloma-A malignant condition characterized by the uncontrolled proliferation and dis- ordered function of plasma cells (a type of white blood cell) in the bone marrow.
That means it involves an overgrowth (proliferation) of lymphatic cells. This makes Castleman disease similar to cancers of the lymphatic system (lymphomas), which also are characterized by cell overgrowth.
MAS results in excessive proliferation and activation of specific white blood cell types; T-lymphocytes and macrophages. MAS results in high fever, organ enlargement, anemia, and difficulty with coagulation of the blood.
The challenge is to learn which mutations are critical to causing cell proliferation, co-author Maxson explained. "We're working to try to understand which of the mutations drive the cancer and which are just passengers in the car," she said.
The hormone, oestrogen is responsible for growth and proliferation of uterine tissue. Women who have diabetes or endometrial polyps or who are taking hormone replacement therapy are more susceptible for endometrial cancer.
Immunoproliferative Disorders - Disorders characterized by abnormal proliferation of primary cells of the immune system or by excessive production of immunoglobulins.
Immunologic Diseases Definitions and Terms ...
Any of various acute or chronic neoplastic diseases of the bone marrow in which unrestrained proliferation of white blood cells occurs, usually accompanied by anemia, impaired blood clotting, and enlargement of the lymph nodes, liver, and spleen.
Abnormal atypical cellular proliferation, but not yet advanced enough to be called neoplasia. Usually a forerunner to neoplasia.
Periaqueductal Gray [matter]; Polyacrylamide Gel; Pregnancy-associated Globulin; Proliferation-associated Gene; Proximal Anastomosis Graft; Pulmonary Arteriography
Basle Nomina Anatomica; Bronchoscopic Needle Aspiration ...
The enlargement of an organ or tissue by the proliferation of cells of an abnormal type.
Glossary 2.7 uses technologies including PHP and SQL ...
do not transmit sinus infections; most clinicians agree that except for rare instances, sinus infections are not contagious but arise from mainly viruses and bacteria that, by chance, contaminate a person who sinuses support their proliferation ...
Cancer: Caused by problems with cell proliferation. There are more than 200 different types of cancer.
Glutamine is believed to facilitate gastrointestinal function, such as helping to maintain healthy gut barrier function, intestinal cell proliferation and differentiation, and reducing septic morbidity.
Histiocytosis, sinus: A variant of histiocytosis in which the lymph nodes are the main site of histiocyte proliferation. The sinuses become filled with and distended by masses of histiocytes.
See also histiocytosis.
One of the reasons for the rapid proliferation of groups focusing on health problems may be the advent of managed health care.
Several factors can lead to this abnormal proliferation of cells, including: ...
The delicate, hazy, tan macular rim of this lesion, although not clinically dramatic, represents persistent melanocytic proliferation beyond the lateral limits of the common mole at its center.
Nodular Melanoma ...
The follicular phase includes the time when menstruation occurs and is followed by proliferation or the growth and thickening of the endometrium. This phase typically lasts from 10 to 14 days, starting with the first day of menstruation.
Histiocytosis: A disease in which histiocytes are the principal cells involved. Langerhans cell histiocytosis is a neoplastic proliferation of histiocytes that involves the skin, bone, brain and other organs.
Hyperplasia: An abnormal increase in the number of cells in a specific area, such as the lining of the breast ducts or the lobules. By itself, hyperplasia is not cancerous, but when the proliferation (rapid growth) is marked and/or the cells are ...
Isovaleryl-CoenzymeA Disintegrin and Metalloprotease ProteinsA FiberA FibersA gamma GlobinA gamma-GlobinA GeneA GenesA Hydratase, trans-2-Enoyl-CoenzymeA Kinase Anchor ProteinsA Ligases, CoA Ligases, CoenzymeA Polymerase, PolyA Proliferation Inducing ...
Lee, B-S, Margolin, SB, Nowak, RA. "Perdfenidone: A Novel Pharmacological Agent that Inhibits Leiomyoma Cell Proliferation and Collagen Production." Journal of Clinical Endocrinology and Metabolism. 1998; 83(1); 219-223.
Note: VIN is not a cancer. The word neoplasia is sometimes used when talking of various cancers but its strict definition is an abnormal proliferation of cells. With VIN the cells are not cancerous.
Kidneys and spleen swollen.
Microscopically - focal necrosis, bile duct proliferation and inflammation.
- Calcium supplements (2000 mg) provide a marked suppression of rectal cancer proliferation. It inhibits early stages of colon cancer in genetically vulnerable individuals.
A cherry hemangioma is a small non-cancerous, red-purple bump on the skin that is typically seen in older adults. It is formed from a proliferation of dilated small veins.
Chickenpox (Varicella) ...
Viruses and retroviruses are parasitic on host cells, causing cellular degeneration, as in rabies, poliomyelitis, and AIDS, or cellular proliferation, as in warts and cold sores.
Phlebitis - A painful swelling of the vein.
PI 3-kinase - An enzyme that plays a crucial role in cell proliferation and survival.
glioblastoma multiforme WHO grade IV astrocytoma characterized by hemorrhagic necrosis, endothelial proliferation, ± crossing of the corpus callosum, ring-enhancement on imaging, and poor survival ...
tumor - an abnormal benign or malignant new growth of tissue that possesses no physiologic function and arises from uncontrolled usually rapid cellular proliferation.
Multiplying or increasing in number. In biology, cell proliferation occurs by a process known as cell division.
See also: Cancer, Tumor, Surgery, Death, Breast Cancer