Richter syndrome (RIK-ter SIN-drome) A rare condition in which chronic lymphocytic leukemia (CLL) changes into a fast-growing type of lymphoma. Symptoms of Richter syndrome include fever, loss of weight and muscle mass, and other health problems.
[9] Transformation of CLL to diffuse large cell lymphoma (Richter syndrome) carries a poor prognosis with a median survival of less than 1 year, though 20% of the patients may live more than 5 years after aggressive combination chemotherapy.
"Richter syndrome: biology, incidence, and therapeutic strategies. PMID 15578683 "
^ Monoclonal B lymphocytes with the characteristics of "indolent" chronic lymphocytic leukemia are present in 3.
 See also: Aging, Symptom, Leukemia, Infections, Lymphoma
  
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