More on Scrapie
Prion - unidentified infectious agent thought to cause a group of diseases known as prion diseases or transmissible spongiform encephalopathies. Well-known prion diseases are Creutzfeldt-Jakob dis...
Scrapie: a transmissible nervous disease in sheep and goats with an incubation period of between two and four years. Known in Europe since the 18th century.
Scrapie
A fatal disease of sheep characterized by chronic itching and loss of muscular control and progressive degeneration of the central nervous system. [Wordnet]
Screwworm Myiasis ...
BSE is a progressive neurological disorder in cattle similar to a disease in sheep called scrapie. BSE has been found primarily in cattle in the United Kingdom, but also in other areas of Europe. It has not been found in U.S.
ADI, ADA, Drug Surveillances, Postmarketing, Dynein ATPase, Endocardium, Family Physician, Fibrils, Scrapie-Associated, Finger, Clubbed, Footprinting, Protein, Frostbites, Galactosylceramide-beta-Galactosidase Deficiency Disease, Genes, Archaeal, ...
By 1986, BSE was recognized as a transmissible spongiform encephalopathy (TSE) of cattle and considered to be analogous to scrapie, a disease of sheep that is not known to cause human disease.
The most widespread TSE in animals is scrapie, a disease that has affected sheep and goats since the mid-18th century.
BSE possibly originated as a result of feeding cattle meat-and-bone meal that contained BSE-infected products from a spontaneously occurring case of BSE or scrapie-infected sheep products. Scrapie is a prion disease of sheep.
The transmission of the naturally occurring TSE scrapie in sheep to cattle through the food chain is believed to have caused the epidemic of BSE in the United Kingdom in the 1980s. BSE has not occurred in Australian cattle.
Prions are very unique proteins which appear to be responsible for a family of illnesses collectively referred to as Transmissible Spongiform Encephalopathies (TSEs), including scrapie in sheep, kuru in humans, and 'mad cow disease' in cows.
These proteins reacted with antibodies raised against the scrapie prion protein PrP 27-30. Rod-shaped particles found in the brain tissue of the patients were similar to those from rodents with either scrapie or experimental CJD.
Manuelidis L, et al. (2007). Cells infected with scrapie and Creutzfeldt-Jakob disease agents produce intracellular 25-nm virus-like particles. Proceedings of the National Academy of Science, 104(6): 1965-1970.
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prion: Infectious particle that is responsible for certain slow-acting diseases such as scrapie in sheep and goats, and Creutzfeldt-Jakob disease in humans.
In addition, there have never been any indications of human illness related to scrapie, a prion disease found in sheep.
BSE (Bovine Spongiform Encephalopathy, or Mad Cow Disease) ... Scrapie is a prion disease of sheep. ... It was in an adult Holstein cow from Washington State. ...
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Secret Agent
Research into BSE and similar diseases (nvCJD, CJD, scrapie) have provided three theories about the agent that causes BSE. These theories lead us to believe that it is: ...
The outbreak may have resulted from the feeding of scrapie-containing sheep meat-and-bone meal to cattle. There is strong evidence and general agreement that the outbreak was amplified by feeding rendered bovine meat-and-bone meal to young calves.
CJD may be related to several other diseases also thought to be caused by prions, including kuru (seen in New Guinea women who ate the brains of deceased relatives as part of a funerary ritual), scrapie (found in sheep), ...
Degenerative disease of the central nervous system found in members of the Fore tribe of new Guinea: a spongiform encephalopathy (prion disease) similar to scrapie and thought to be transmitted by cannibalism.
BSE was discovered in Great Britain in 1995, and is thought to have been caused by the use of cattle feed containing ground meat and bone meal from sheep infected with a prion disease (like BSE and CJD) found only in sheep, called scrapie.
Other TSEs include Creutzfeldt-Jakob disease and fatal familial insomnia in humans, bovine spongiform encephalopathy in cattle (also known as mad cow disease), scrapie in sheep and goats, and chronic wasting disease in deer and elk.
 See also: Prion, Spongiform encephalopathy, Symptom, Creutzfeldt-Jakob Disease, Bovine Spongiform Encephalopathy
  
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