Spherocytosis

Spherocytosis
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Spherocytosis
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Spherocytosis is a condition that causes an abnormality in the red blood cell membrane.

Hereditary spherocytosis is most common in people of northern European ancestry. It often shows up in infancy or early childhood, causing anemia and jaundice. The bone marrow has to work extra hard to make more red cells.

Course of the disease in hereditary spherocytosis
Removal of the spleen (splenectomy) results in striking and usually permanent improvement both in the symptoms and in the anaemia, ...

Alternate Names : Hereditary spherocytosis, Spherocytosis
Definition
Congenital spherocytic anemia is a disorder of the surface layer (membrane) of red blood cells.

Spherocytosis, Hereditary
Related Terms
Chronic Acholuric Jaundice
Chronic Familial Icterus
Chronic Familiar Jaundice
Congenital Hemolytic Anemia
Congenital Hemolytic Icterus
Congenital Hemolytic Jaundice
Congenital Spherocytosis ...

spherocytosis
sfrsa tss noun a condition in which someone has spherocytes in the blood causing anaemia enlarged spleen ...
sphincter ...

Spherocytosis
Thalassemias (α, β-γ)
Undersecretion due to biliary obstruction ...

Hereditary spherocytosis; Spherocytosis
Causes
This disorder is caused by a defective gene. The defect results in an abnormal red blood cell membrane.

hereditary spherocytosis and sickle cell anemia
chronic idiopathic thrombocytopenic purpura (ITP) with failed response to medical treament
hodgkin's disease or chronic leukemia in special situations ...

Hereditary spherocytosis (SFER-o-si-to-sis) is the most common cause of hemolytic anemia among people of Northern European descent.
Hereditary Elliptocytosis (Ovalocytosis) ...

Hereditary spherocytosis
an autosomal dominant disorder, likewise reveals compensatory hyperplasia of the bone marrow with extension of red marrow into the diaphyses of long bones.

Hereditary Spherocytosis: A Patient's Journey

Where Can I Find More Information?

Red blood cells, spherocytosis
Acute lymphocytic leukemia - photomicrograph
Red blood cells, multiple sickle cells ...

Cardiomyopathy -- spherocytosis ... cardiomyopathy, enlarged heart
Cardiomyopathy cataract hip spine disease ... enlarged heart
Cardiomyopathy diabetes deafness ... cardiomyopathy
Cardiomyopathy dilated 10 ... palpitations, abnormal heart rhythm ...

Hereditary spherocytosis a hereditary form of anemia characterized by abnormally shaped red blood cells which are spherical and abnormally fragile.

Spherocytosis
spherophakia-brachymorphia syndrome
Sphingolipidosis 1
Sphingolipidosis, Krabbe's Type
Sphingolipidosis, Tay-Sachs
Spica cast, Caring for your child in a
Spider Bite, Black Widow
Spider Bite, Brown Recluse
Spider Bites ...

Hereditary spherocytosis
Hereditary urea cycle abnormality
Hermaphroditism
Hernia
Hernia - diaphragmatic
Hernia - hiatal
Hernia - inguinal
Herniated intervertebral disk
Herniated nucleus pulposus (slipped disk)
Herniation - brain ...

In children with some types of hereditary anaemia such as sickle cell disease, beta-thalassaemia and hereditary spherocytosis. This virus can cause these types of anaemia to become suddenly much worse.
In people with a weakened immune system.

Dinitrophenyl Compounds, Diploidies, Diseases, alpha-Chain, Drug Administration, Inhalation, Dystrophies, Juvenile Neuroaxonal, Encephalomyelitis, Inflammatory, Epilepsies, Juvenile Absence, FSH Releasing Hormone, Hereditary Spherocytosis, ...

Ankyrin deficiency: Known also as hereditary spherocytosis, a genetic disorder of the red blood cell membrane clinically characterized by anemia, jaundice (yellowing) and splenomegaly (enlargement of the spleen), ...

Hemolytic anemia can be present at birth (congenital hemolytic anemia or spherocytosis) or acquired later in life. It is the result of either infection or the presence of antibodies that destroy RBCs more rapidly than bone marrow can replace them.

Hereditary spherocytosis
Idiopathic autoimmune hemolytic anemia
Malaria
Microangiopathic hemolytic anemia (MAHA)
Non-immune hemolytic anemia caused by chemicals or toxins
Paroxysmal nocturnal hemoglobinuria (PNH) ...

membrane: Hereditary spherocytosis (Minkowski-Chauffard syndrome) Â- Hereditary elliptocytosis (Southeast Asian ovalocytosis) Â- Hereditary stomatocytosis
Acquired
Autoimmune (WAHA, CAD, PCH) ...

the RBC osmotic fragility test (which mixes RBCs with varying concentrations of saline), the RBC autohemolysis test (which measures the amount of spontaneous hemolysis occurring after 48 h of sterile incubation), and, to rule out spherocytosis due to ...

Sickle cell disease, thalassemia, and spherocytosis are examples of diseases that form unusually shaped cells that cannot easily maneuver through the small blood vessels and capillaries of the body.

Risk factors for pigment stones include chronic hameolysis (red blood cell breakdown) -hereditary spherocytosis, sickle cell disease, as well as liver cirrhosis.

blood cell disorders (sickle cell anemia, thalassemia, spherocytosis);
Inflammatory disease (lupus, rheumatoid arthritis);
idiopathic thrombocytopenic purpura (ITP); and ...

Congenital Nonspherocytic Hemolytic Anemia includes any of a group of inherited anemias characterized by shortened red cell survival, lack of spherocytosis, and normal osmotic fragility associated with erythrocyte membrane defects, ...

Secondary Pulmonary Hemosiderosis; Severely And Profoundly Handicapped; Spherocyte; Spherocytosis; Sphingomyelin
PPHN
Persistent Pulmonary Hypertension Of The Newborn ...

Haemolytic blood disorders those with disorders such as sickle cell anaemia, thalassaemia and hereditary spherocytosis can experience a sudden drop in haemoglobin, the protein that transports oxygen around the blood.

Genetic causes of hemolytic anemia include conditions like sickle cell anemia. Other conditions that can create hemolytic anemia are often rare disorders like spherocytosis, a disorder of the spleen, or elliptocytosis, ...

Anaemia resulting from reduced red cell survival time and haemolysis, either due to an intrinsic defect in the erythrocyte (hereditary spherocytosis or ellipsocytosis, enzyme defects, haemoglobinopathy) or an extrinsic damaging agent.

Thalassemia
Anemia due to glucose-6-phosphate-dehydrogenase deficiency
Hereditary spherocytosis
Autoimmune hemolytic anemia
Microangiopathic hemolytic anemia
Pernicious anemia
Sickle cell anemia ...

hereditary spherocytosis, a condition in which part of the blood cells take on a spherical shape causing jaundice and anemia
leukemia, or cancer of the blood cells
traumatic injury
blood clots that get into the spleen ...

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These cells are more rigid than normal, and they become targets for the spleen, which identifies them as abnormal and removes them from circulation. These illnesses include hereditary spherocytosis, hereditary elliptocytosis, ...

Hemolytic anemias -- cells are destroyed
Red blood cells are also destroyed in Sickle Cell Anemia, hereditary diseases, spherocytosis, thrombocyopenic purpura, hemolytic-uremic syndrome, and G6PD deficiency
Drug induced hemolytic anemia ...

Hereditary Spherocytosis
Hereditary Type I Hypophosphatemia (HPDR I)
Hereditary Type II Hypophosphatemia (HPDR II)
Hereditary tyrosinemia type 1
Hereditary Unconjugated Hyperbilirubinemia
Heredopathia Atactica Polyneuritiformis ...

See also: Deficiency, Symptom, Cancer, Sickle Cell, Anemia