Thrombasthenia

Glanzmann's thrombasthenia is a condition caused by the lack of a protein required for platelets to clump together. This disorder may also cause severe bleeding.

Thrombasthenia
Reviewed last on: 2/7/2007
William Matsui, MD, Assistant Professor of Oncology, Division of Hematologic Malignancies, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD.

Thrombasthenia
Causes
Glanzmann's disease is caused by lack of a protein required for platelets to clump together (aggregate) normally.

Thrombasthenia
Causes, incidence, and risk factors
Glanzmann’s disease is caused by lack of a protein required for platelets to clump together (aggregate) normally.

Glanzmann's thrombasthenia is a rare inheritable disease in which the body's normal blood clotting system has a defect characterised by a problem with platelet-mediated haemostasis, and blood does not clot.

Glanzmann Thrombasthenia
Glanzmann Thrombasthenia, Type A
Glanzmann-Naegeli Syndrome
glatiramer (injection) - Medication
Glatiramer for multiple sclerosis - Medication
Glaucoma
Glaucoma Research Foundation - Support Group ...

Glanzmann Thrombasthenia
Glanzmann Thrombasthenia
Glanzmann Thrombasthenia, Type A
Glanzmann-Naegeli Syndrome
Glaucoma
Glaucoma Screening
Glaucoma Surgery: Which Eye First?
Glaucoma, Goniotomy for
Glaucoma, Iridotomy (Laser) for ...

Thrombasthenia ... excessive menstrual bleeding, abnormally heavy or long menstrual periods, abnormally heavy or long menstrual periods
Thrombocytopathy ... excessive menstrual bleeding
Thrombocytopenia ... vaginal bleeding ...

Deferoxamine B, Deficiency Diseases, Glucocerebrosidase, DNA Transposons, Electrostimulation, Programmed, Elephantiases, Filarial, Galanthamine Hydrobromide, Glanzmann Thrombasthenia, Hyperpituitarism, Infusion Therapies, Home, Inhibitors, ...

Glanzmann's Thrombasthenia
Glaucoma
Gliomas see Brain Tumours
Global Developmental Delay
Glomerulonephritis
Glutaric Aciduria Type II see Fatty Acid Oxidation disorders
Glycogen Storage disease Type II see Pompe disease
Glycogen Storage diseases ...

Glanzmann's thrombasthenia
Glanzmann's disease
Glaucoma
Glioblastoma multiforme - adults
Glioblastoma multiforme - children
Glioma - adults
Glioma - children
Glioma - optic
Globoid cell leukodystrophy
Glomerulonephritis ...

Gene Transfer Agent; Glanzmann Thrombasthenia; Glycerol Teichoic Acid
GAA
Guanine-adenine-adenine Codon For Glutamic Acid ...

adhesion (Bernard-Soulier syndrome) Â- aggregation (Glanzmann's thrombasthenia) Â- platelet storage pool deficiency (Hermansky-Pudlak syndrome, Gray platelet syndrome)
Clotting factor ...

Disseminated intravascular coagulopathy (DIC)
Factor XIII deficiency
Glanzmann's thrombasthenia
Hypoprothrombinemia
Liver disease ...

The genetic deficiency in platelet membrane glycoprotein Ib allows platelets to aggregate normally (c.f. Glanzmann's thrombasthenia) but they do not stick to collagen of sub endothelial basement membrane.

See also: Asthenia, Deficiency, Cancer, Symptom, Surgery