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Thymoma

Disease  Thymic carcinoma  Thyroid cancer

Thymomas are rare tumors of the thymus gland. Rarely, other tumors such as lymphomas, leukemias and germ cell tumors can be found in the thymus gland. The commonest age to be diagnosed with a thymoma is between 40 and 60 years. Most thymomas are slow-growing tumors.


Thymoma and thymic carcinoma
This information is about tumours that affect the thymus gland.
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About thymoma
Cancer begins when normal cells change and grow uncontrollably, forming a mass called a tumor. A tumor can be benign (noncancerous) or malignant (cancerous, meaning it can spread to other parts of the body).

Thymoma and Thymic Carcinoma Treatment
[ patient ] [ health professional ]
Metastatic Cancer
Clinical Trials
Information and current news about clinical trials and trial-related data ...

Alternate Names : Thymoma - mediastinal, Lymphoma - mediastinal
Definition
Mediastinal tumors are growths that form in the area that separates the lungs. This area contains the heart, large blood vessels, windpipe (trachea), thymus gland, and connective tissues.

Thymoma
Main article: thymoma
Most common primary anterior mediastinal tumor (20%) in adults but rarely seen in children. It can be classified as lymphocytic, epithelial, or spindle cell histologies, but the clinical significance of these classifications is controversial.

Thymoma
Our experts provide a thorough evaluation and personalized treatment for patients diagnosed with thymoma.
Thyroid Cancer ...

thymoma A tumor of the thymus, an organ that is part of the lymphatic system and is located in the chest, behind the breastbone.
thymus An organ that is part of the lymphatic system, in which T lymphocytes grow and multiply. The thymus is in the chest behind the breastbone.

Thymoma - mediastinal; Lymphoma - mediastinal
Updated by: Benjamin Medoff, MD, Assistant Professor of Medicine, Harvard Medical School, Pulmonary and Critical Care Unit, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Thymoma - a tumor of the thymus gland (located behind the breastbone, the thymus is part of the immune system)
By determining the stage of lung or mediastinal cancer, if present, the physician can plan for additional surgical procedures or other types of treatment.

Individuals with thymoma only or MG-related thymoma will require regular, detailed follow-up examinations and possible chemotherapy or radiotherapy. Time must be allowed for follow-up treatment of this type and an appropriate recovery period after each treatment.

Also called type C thymoma.
Permalink for thymic carcinoma
thymidine A chemical compound found in DNA. Also used as treatment for mucositis.
Permalink for thymidine ...

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Thyroid - Graves' Disease and Thyroid Foundation - Support Group ...

My 67-year-old wife has been diagnosed with what appears to be a thymoma according to her CT and PET scans. We have seen doctors at Moffitt in FL, where we live and a thoracic surgeon at Sloan-Kettering and M.D. Anderson.

Critical pathologic evaluation of mediastinal tumors is essential, because a variety of neoplasms with specific therapeutic implications can arise in this location (eg, mediastinal germ cell tumor, lymphoma, thymoma).

Thymectomy Trial in Non-Thymomatous MG Patients Receiving Prednisone Therapy
This trial determines if thymectomy combined with prednisone therapy is more beneficial in treating non-thymomatous MG than prednisone therapy alone
More Information »
See All Trials » ...

The cause is not known but it tends to develop in some people who have a thymoma (a growth of the thymus gland), systemic lupus erythematosus (SLE) - also known as lupus - or thyrotoxicosis (overactive thyroid).
A rare side-effect of some medicines and a rare complication of various diseases.

Chest CT scan is done to investigate the thymus as 10 per cent of patients with MG have a tumour of the thymus (a thymoma) that is usually benign. The thymus is part of the immune system and is a tissue situated in the middle of the chest, behind the breastbone.

In the 15 percent of people with myasthenia gravis who have a thymoma, the tumor needs to be removed due to its potential transformation into a malignancy. Thymectomy, the surgical removal of the thymus gland, can reduce symptoms in those individuals with or without thymomas.

Scientific evidence links interactions between thymoma function, thymoma, and pemphigus, often associating loss of self-tolerance and the presence of autoimmunity.[20] The association of pemphigus foliaceus and thymoma is noteworthy.

The differential includes lymphoma, thyroid malignancy, thymoma and teratoma and the age of the patient and accompanying clinical symptoms and signs would help order the list.
I would notify the referring clinician urgently and suggest a CT scan to assist diagnosis and assess the extent of disease.

Some people with myasthenia gravis turn out to have a thymoma (a tumour in the thymus). This is a type of cancer, but very few people die of thymomas (see "Treatment and Prevention").
Symptoms and Complications of Myasthenia Gravis ...

Examples of ectopic sites include thymoma, medullary carcinoma of the thyroid, pheochromocytoma, islet cell tumours of the pancreas and oat cell carcinoma of the lung.

Pemphigus vulgaris may be occurs in patients due to other autoimmune diseases, particularly myasthenia gravis and thymoma.
Pemphigus may also be occur due to reactions to medications, although this is rare.

A rare tumor of the thymus gland called a "thymoma"
Symptoms affect many muscles
How does JMG affect chewing and swallowing?

Family members with pemphigus
A history of having autoimmune diseases, such as myasthenia gravis , lupus , or thymoma
Age: middle to late adulthood
Jewish or Mediterranean descent
Regular use of certain drugs, including: ...

Cancer Chemotherapy
Radiation therapy
Pregnancy
Some forms may be associated with thymomas (the types that only affect red blood cells) ...

Myasthenia can occur in association with other autoimmune diseases most commonly thyroid disease, rheumatoid arthritis, and diabetes. A thymoma in the chest cavity is another association.
How is myasthenia gravis treated?

sarcoidosis - a condition that causes small, fleshy, swellings in the tissue around organs, usually in the liver, lungs, and spleen
thymoma - a tumor of the thymus gland (located behind the breastbone, the thymus is part of the immune system) ...

Tensilon test-a dose of a medication called edrophonium chloride is given, which will briefly improve muscle weakness
CT or MRI scan of the chest-to look for a tumor of the thymus gland (thymoma)
Pulmonary function testing -to assess how MG may be affecting your ability to breathe ...

In the nitrite-supplemented diet study only, the incidence of benign lymphocytic thymoma was increased in all treated groups of females. It was not determined if the nitrosated product is systemically absorbed. However, no changes were seen in the stomachs of rats in that study.

See also: See also: What is the meaning of Tumor, Cancer, Surgery, Immune System, Asthenia?

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