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Transfusion reaction

Disease TrachomaTransient familial hyperbilirubinemia

Transfusion reaction - hemolytic
Alternate Names : Blood transfusion reaction
Definition ...

 


What is Transfusion reactions?
Blood transfusion is associated with a number of potential side effects. These include:
Fever
Allergic reaction
Acute haemolysis (immediate breakdown of red blood cells) ...

Transfusion reaction
In medicine, a transfusion reaction is any adverse event which occurs because of a blood transfusion.

Transfusion reaction is a problem that occurs after a patient receives blood. The immune system launches a response against the new blood cells or other parts of the transfusion.
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Blood Transfusion Reaction
Mediated by immune or nonimmune factors, a transfusion reaction accompanies or follows I. V. administration of blood components.

Symptoms of BLOOD-TRANSFUSION REACTION
View symptom groups below that present with BLOOD-TRANSFUSION REACTION
Overview and causes of BLOOD-TRANSFUSION REACTION - click here ...

Transfusion Reactions
Due to the presence of isoantibodies against non self blood group antigens, individuals of type A blood group immediately raises anti-B antibodies against B-blood group RBCs if transfused with blood from B group.

Transfusion reaction - hemolytic
Acute tubular necrosis is a kidney disorder involving damage to the tubule cells of the kidneys, resulting in acute kidney failure.
Causes ...

Transfusion reactions occur when the blood you are given does not match your blood type. This matching error is rare. The lab may mislabel a unit of blood. A doctor, nurse, or technician may misread the label before the blood is given to you.

Transfusion reactions are usually minor, and caused by antibodies to white blood cells still present in the blood product. This occurs in about 1 to 2% of all transfusions. Most reactions slowly clear after the transfusion is stopped.

Transfusion reactions
Urticaria usually within a few minutes after initiating blood product transfusion (or switching to a new unit of blood product)
Clinical evaluation ...

Transfusion reactions, which can be caused by the surface antigens of neutrophilia; recipients of repeated granulocyte transfusions could become alloimmunized
Large granular lymphocyte proliferation or leukemia ...

Blood transfusion reaction
Cancer, including leukemia
Infection in the blood by bacteria or fungus
Pregnancy complications (such as retained placenta after delivery)
Recent surgery or anesthesia
Sepsis (an overwhelming infection)
Severe liver disease ...

Blood transfusion reaction
Injury or trauma that damages the muscles
Recent major surgery
Septic shock or other forms of shock
Severe low blood pressure (hypotension) that lasts longer than 30 minutes ...

Blood transfusion reaction
Cancer, especially certain types of leukemia
Infection in the blood by bacteria or fungus
Liver disease
Pregnancy complications (such as placenta that is left behind after delivery)
Recent surgery or anesthesia ...

One complication that may occur is a reaction to an incompatible blood type (transfusion reaction, ABO incompatibility, hemolytic reaction). Symptoms include chest pain, trouble breathing, fever and chills, and low blood pressure.

Individuals can develop reactions to certain proteins in the blood-called a transfusion reaction. This can make locating appropriately matched donor blood more difficult.

Immunologic blood transfusion reactions
Indications for red cell transfusion in the adult
Iron requirements and iron deficiency in adolescents
Laboratory testing of donated blood
Leukoreduction to prevent complications of blood transfusion ...

With all transfusions there is the potential of having a transfusion reaction. To prevent this, all patients will receive tylenol and benadryl before the transfusion.

The blood type of the donor and the recipient must be matched to prevent a transfusion reaction, a potentially fatal condition. This is done in the hospital laboratory and is called 'type and cross-match.

Care must be taken if blood transfusion is required, as transfusion reactions can occur following repeated transfusion of blood with kell antigens (as most people have).

Blood transfusion reaction
Cellulitis
Conjunctivitis (inflammation of the eye)
Drug reactions, including those due to aspirin, penicillin, sulfa, glucocorticoids, and others
Head, nose, or jaw surgery ...

Transfusion reactions - a form of allergic response - may hamper the smooth running of a transfusion or cause it to be abandoned completely.

If you get blood in a transfusion that isn't the right type, you may have a transfusion reaction. A mild transfusion reaction rarely is dangerous, but you must get treatment quickly. A severe transfusion reaction can be deadly.

Huh YO, Lichtiger B: Transfusion reactions in patients with cancer. Am J Clin Pathol 87 (2): 253-7, 1987.
Marchetti O, Calandra T: Infections in neutropenic cancer patients. Lancet 359 (9308): 723-5, 2002.
Quesada JR, Talpaz M, Rios A, et al.

Transfusion Reaction ... Back pain
Transitional cell carcinoma ... back pain
Transverse myelitis ... lower back pain, back pain
Tubulointerstitial nephritis and uveitis ... lower back pain
Type I spinal osteoporosis ... back pain ...

ABO incompatibility: A type of blood incompatibility, found rarely. Transfusion reactions may occur as a result of such incompatibility
Aborad: In a direction away from the mouth; opposite of orad.

Examples of these types of allergic reactions are transfusion reactions, autoimmune hemolytic anemia.

sickle cell anemia (or any other type of hemolytic anemia),
a transfusion reaction (due to an immune response against transfused red blood cells),
thrombotic thrombocytic purpura (TTP), and
tuberculosis of the urinary tract.

Transfusion reaction
Transient familial hyperbilirubinemia
Transient ischemic attack
Transient monocular blindness
Transient RDS
Transient synovitis
Transient tachypnea - newborn
Transient tic disorder ...

See also: Fusion, Symptom, Blood Transfusion, Kidney, Bleeding