Urea Cycle Disorders

Urea cycle disorders

Urea cycle disorders are conditions in which the body cannot properly dispose of ammonia, a waste product of protein digestion.

Urea cycle disorders can result from decreased activity of any of the following enzymes: N-acetylglutamate synthetase (NAGS), carbamyl phosphate synthetase (CPS), argininosuccinate synthetase (ASS), ornithine transcarbamylase (OTC), ...

Urea cycle disorders are characterized by hyperammonemia under catabolic or protein-loading conditions.

The urea cycle disorders are a group of rare disorders affecting the urea cycle, a series of biochemical processes in which nitrogen is converted into urea and removed from the body through the urine. Nitrogen is a waste product of protein metabolism.

Gene Reviews: Urea Cycle Disorders Overview
Gene Tests: Carbamoylphosphate Synthetase I Deficiency
MedlinePlus Encyclopedia: Hereditary urea cycle abnormality ...

Most patients with urea cycle disorders will need to stay in the hospital at some point. During such times, they may be treated with medicines that help the body remove nitrogen-containing wastes.

National Urea Cycle Disorders Foundation - Support Group
National Urea Cycle Disorders Foundation - Urea Cycle Disorders - Support Group
National Vaccine Information Center - Support Group ...

N-acetyl Glutamate Synthase Deficiency see Urea Cycle Disorders
Naevus Flammus see Vascular Birthmarks
Nager syndrome
NAGS Deficiency see Urea Cycle disorders
Nail-Patella syndrome
Narcolepsy
NBCCS see Gorlin syndrome
Necrotising Fasciitis ...

See also: Urea Cycle, Deficiency, Symptom, Ammonia, Vomiting