XXY Males

XXY males can have normal sex lives, but they usually make little or no sperm. Between 95 percent and 99 percent of XXY males are infertile because their bodies don’t make a lot of sperm.

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In recent years, many XXY males have been diagnosed before birth, through amniocentesis or chorionic villus sampling (CVS).
The next most likely opportunity for diagnosis is when the child begins school.

Many men with an extra X chromosome are not aware that they have it, and they lead normal lives. Males who have Klinefelter syndrome may be described as XXY males or males with XXY syndrome. Klinefelter syndrome occurs in about 1 out of 1,000 males.

Type I (papillon-leage and psaume syndrome, gorlin-psaume syndrome) is inherited as an x-linked dominant trait and is found only in females and XXY males. Type II (mohr syndrome) is inherited as an autosomal recessive trait.

See also: Symptom, Klinefelter syndrome, Fertility, Trisomy, Amniocentesis