maximum tolerated dose (MTD)
High dose used in chronic toxicity testing that is expected on the basis of an adequate subchronic study to produce limited toxicity when administered for the duration of the test period.
Note 1: It should not induce: ...
Maximum Tolerated Dose
The maximum dose that an animal species can tolerate for a major portion of its lifetime without significant impairment or toxic effect other than carcinogenesis.
Measure of Effect/ Measurement Endpoint ...
 See also: Environmental, Bacteria, Concentration, Liquid, Contaminant
  
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