One-hit Model
A mathematical model based on the biological theory that a single "hit" of some minimum critical amount of a carcinogen at a cellular target such as DNA can start an irreversible series events leading to a tumour.
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one-hit model
Dose-response model of the form
P =1 - e-bd
where P is the probability of cancer death from a continuous dose rate, d, and b is a constant.
multistage model Mathematical model based on the multistage theory of the carcinogenic process which yields risk estimates either equal to or less than the one-hit model.
 See also: Development, Concentration, Organic, Pollutant, Air
  
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