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This disorder is a neural tube defect and involves incomplete development of the brain, spinal cord, and/or their protective coverings. The neural tube is a narrow sheath that folds and closes between the 3rd and 4th weeks of pregnancy to form the brain, skull, and scalp.
There is good evidence now that women who have had a baby with anencephaly or spina bifida should take higher dose folic acid in subsequent pregnancies and that this considerably reduces the risk of a second baby being affected.
anencephaly -- a type of neural tube disorder where the baby's brain does not form. This is caused by a failure of the neural tube to close properly very early in the baby's development. Anencephalic babies often die prior to birth, but can live a few hours after being born.
Anencephaly: A neural tube defect involving severe structural defects of the brain and skull. Fetuses with anencephaly do not survive.
Anesthesia: Loss of sensation, or general insensibility to pain, induced by an anesthetic.
~: Defective development of the brain combined with the absence of the bones normally surrounding the brain.
Angioma: Tumor, usually benign, or swelling composed of lymph and blood vessels.
Anovulatory: Lack of or cessation of ovulation.
~ - A birth defect resulting in the abnormal development of the baby's brain and skull.
Anesthesia - A partial or complete loss of sensation or consciousness, with absence of pain sensation, produced by an anesthetic
Antepartum - Before labor or childbirth ...
~: A neural-tube defect wherein the baby’s skull and brain do inside the uterus. The baby usually remains alive while growing inside the uterus, but dies soon after birth.
~: A severe congenital defect in which the fetus has no brain.
Anesthesia: Medically induced loss of sensation. General anesthesia involves the entire body; local anesthesia involves only a particular area.
Anomaly: Malformation or abnormality of a body part.
~: This is the most severe form of Spina Bifida and affected babies have a high mortality rate. Still birth or death shortly after birth is the expected outcome. This is because anencephaly is the result of minimal brain development. The cerebrum might only part-develop, or not at all.
~ - Defect resulting in the absence of most of the brain and spinal cord.
Anesthesia - A medication that causes unconsciousness or a loss of general sensation.
Anesthesiologist - A specialist that administers anesthetic's to a patient.
A birth defect resulting in the absence of a major portion of the skull and brain. ~ results when the upper portion of the neural tube fails to close. The condition is not compatible with life, and infants usually die within a few days after delivery. See picture ...
~: A rare birth defect in which the baby has a malformed skull and little or no brain.
Anesthesia: A general term describing techniques to ease pain. Types of anesthesia often used during childbirth include local anesthesia, general anesthesia, or analgesia.
One of several neural tube defects. The neural tube is a embryonic structure in the developing fetus that forms the spinal cord and brain. ~ is caused by failure of the upper end of the neural tube (the rostral neuropore) to close in the embryo's fourth week of life.
~ and spina bifida are the two most common NTDs. ~ is a fatal condition in which the upper end of the neural tube fails to close. In these cases, the brain fails to develop completely or is entirely absent.
~ (Complementary/Alternative Medicine)
Antibiotics for Mastitis While Breast-Feeding
Antibiotics to Treat and Prevent Infection During Preterm Labor ...
Babies with anencephaly usually do not live long, and those with spina bifida may be permanently disabled. These are scary problems, to say the least. But the good news is that getting enough folic acid may protect your baby from neural tube defects by at least 50%.
We had a history of anencephaly in our family, and had had the AFP test with Hilary. SInce it came back saying that everything was fine, we didn't even question wether or notto do it again.
The natural history of anencephaly.
Prenat Diagn, 30(4): 357-60. [Abstract] [Full-text]
Association between dietary calcium and vitamin D intake and cervical carcinogenesis among Japanese women.
Eur J Clin Nutr, 64(4): 400-9. [Abstract] [Full-text] ...
You reduce your chances of giving birth to a baby with a neural tube defect (for example, anencephaly or spina bifida) by 50% to 70% if you start taking at least 0.4 mg of folic acid each day two to three months before you start trying to conceive.
Two common tubal defects are: Spina bifida, which results when the column surrounding the spinal cord is not formed, and anencephaly, which occurs when the brain is not completely formed.
Congenital Hip Dislocation: The hipbone in some children may be improperly placed within the pelvic socket.
Alpha fetoprotein: a protein produced by the baby that can be measured prenatally, by taking a tube of your blood, to identify possible neural tube disorders and other potential problems, such as Down's Syndrome or anencephaly. A similar test is the triple screen.
absence of the top of the head (anencephaly): 98 per cent
cleft lip: 75 per cent
defect of the abdominal wall, where the bowel and liver protrude (exomphalos): 80 per cent
defect of the abdominal wall, where the intestines protrude (gastroschisis): 98 per cent ...
It is possible to detect neural tube defects, including anencephaly, spina bifida, and meningomyelocele (though the use of amniocentesis to detect neural tube defects has been mostly superceded by a combination of the AFP test and high resolution detailed ultrasound).
The technical names of the two major neural tube birth defects reduced by adequate folate intake are anencephaly and spina bifida. Babies with anencephaly do not develop a brain and are stillborn or die shortly after birth.
She has had a baby with spina bifida or anencephaly and wants to get pregnant again. She should talk with her doctor, and ask for a prescription for a higher dose of folic acid.
There are two main birth defects that folic acid helps to prevent: Spina bifida and anencephaly. Spina bifida is a condition in which the spinal cord doesn't fully develop; it results in permanent disability.
Folic acid deficiency is linked to such neurologic birth defects as spina bifida and anencephaly. In order to prevent these disorders, this B vitamin must be present in the body during the first six weeks following conception, a crucial early phase in fetal neurological development.
Other forms of birth defect, such as anencephaly, which is a serious incomplete development of the brain, and encephalocele, which is when brain tissue abnormally protrudes through an opening in the skin, can also be reduced through adequate folic acid intake.
It can detect such problems as spina bifida, anencephaly and possibly Down's Syndrome. If the test comes back as abnormal, you can have it confirmed with another AFP test or it's possible your provide may recommend you have amniocentesis. Risks of AFP are small.
Using a combination of MSAFP screening and ultrasonography, almost all cases of anencephaly can be found and most cases of spina bifida.
Folic acid (Folate)
folic; acid; folate; spina; bifida; neural; tube; defects; ~; pregnancy; pregnant;
How to get more folate
Folate in food
For more information ...
Unusually high AFP levels are associated with an increased risk of a neural tube defect such as spina bifida or ~, whereas unusually low levels (along with low levels of estriol and high levels of hCG) are related to an increased risk of a chromosomal abnormality such as Down syndrome.
If the neural tube does not close at the top, the baby will have ~ (without a brain). If the neural tube does not close at the bottom, the baby will have spina bifida. Getting enough folate (400 micrograms/day) can help reduce the risk of neural tube defects.
Over a three year period, 27 babies were born with neural tube defects, including ~, spina bifida, and encephalocele. It is currently unknown if this is something more than a statistical blip, but it sure sounds suspicious. (SOURCE: MedPage Today) ...
While researchers don't know why folic acid helps prevent birth defects, it has been shown to decrease the risk of the most common NTDs: spina bifida (the leading cause of childhood paralysis) and ~ (a fatal condition in which an infant is born with a severely underdeveloped brain and ...
Also, without enough folic acid, your baby's brain may not form or may only partly form -- a condition called ~. All of these defects occur during the first 28 days of pregnancy -- usually before a woman even knows she's pregnant.
Elevated MSAFP correlates with different fetal anomalies such as neural tube defects (~ and spina bifida) and abdominal wall defects. It is also associated with fetal death, multiple gestations, and certain abnormalities of the placenta.
Conditions such as ~, where part of the fetal brain is missing, result in death within days of birth; some parents choose to terminate the pregnancy early through labor induction if there's no chance that the fetus will survive or if the fetus will be severely damaged.
It can also pick up several hundred other genetic disorders, such as cystic fibrosis, sickle cell disease, and Tay-Sachs disease, as well as neural tube defects (such as spina bifida and ~).
Folic acid is instrumental in preventing neural tube defects (NTDs) - serious birth defects of the spinal cord (such as spina bifida) and the brain (such as ~)." This article gives the facts and details on folic acid during pregnancy.
Research from the March of Dimes found that overweight and obese women were reported to be 30 to 40 percent more likely than healthy-weight women to deliver a baby with a major birth defect, in particular a neural tube defect, which affects the brain (~) or the spine (spina bifida).
This blood test for 4 biochemical markers, (AFP, HCG, estriol, DIA), has a detection rate of 75% - 80% for aneuploidy. It will also detect 80% of open neural tube defects, which is incomplete closure of the fetal spine that can cause spina bifida or ~.
See also: What is the meaning of Pregnancy, Spina bifida, Neural tube, Genetic, Neural Tube Defect?