Choriocarcinoma
The most dangerous form of GTD. If untreated, it is often swiftly fatal, with distant metastases in the lungs, liver and brain.
Choriocarcinoma: Highly malignant cancer that grows in the uterus during pregnancy or at the site of an ectopic pregnancy.
Chorion: Outermost fetal membrane found around the amnion.
Choriocarcinoma: An extremely rare cancer that grows in the uterus during pregnancy.
Choriocarcinoma most commonly follows a molar pregnancy but can follow a normal pregnancy, ectopic pregnancy, or abortion, and should always be considered when a patient has continued vaginal bleeding in the postdelivery period.
Choriocarcinoma - An uncommon malignant tumor of the placenta that is usually found in the uterus after pregnancy. Cancer cells grow in the tissues that are formed in the uterus after conception and can spread to the lungs.
Massive fetomaternal hemorrhage caused by an intraplacental choriocarcinoma: a case report.
Case Report Med, 2010: 767218. [Abstract] [Full-text] ...
This is a pregnancy-related disorder that includes hydatidiform mole, invasive mole (chorioadenoma destruens), and choriocarcinoma. Hydatidiform mole, the most common, is a tumor of the placenta that is usually benign.
False positive results can result from diseases like choriocarcinomas, IgA deficiencies, heterophile antibodies, enterocystoplasties, gestational trophoblastic diseases (GTD), gestational trophoblastic neoplasms (GTN), ...
This is called choriocarcinoma, and spreads to other organs. This can also be successfully treated with chemotherapy (ISSTD 2010).
Placental Pathology Casebook: Asymptomatic Intraplacental Choriocarcinoma Diagnosed on Routine Placental Examination FREE
Kurt Benirschke, Subodh M Lele MD, Sara E Crowder MD & Marjorie R Grafe MD PhD
244 ...
Hydatidiform mole and choriocarcinoma information service
An excellent website with up to date information from one of the UK's two treatment centres for these conditions.
HCG levels are often tested in a woman who may have abnormal tissue growing in her uterus, a molar pregnancy, or a cancer in the uterus (choriocarcinoma) rather than a normal pregnancy.
Though the prognosis for molar pregnancy is excellent, women who have had a molar pregnancy require close follow-up from their doctors, as some women with complete molar pregnancies develop invasive disease or choriocarcinoma.
An invasive mole occurs in approximately 10 to 20 percent of all complete molar pregnancy cases and 6 to 10 percent of all partial molar pregnancy cases. Choriocarcinoma on the other hand takes place in approximately three percent of complete molar ...
Trophoblastic Disease" (GTD) is the name given to the growth of material that originates either from placental tissue left after miscarriage, complete and partial moles, invasive moles, placental-site trophoblastic tumours or choriocarcinomas.
The absence of a fetus on ultrasonography along with an elevated HCG suggests a hydatidiform mole. The HCG level can be used to follow up treatment for molar pregnancy to make sure that no trophoblastic disease, such as a choriocarcinoma, persists.
 See also: Pregnancy, Pregnant, Placenta, Uterus, Tissue
  
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