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Monosomy

Pregnancy & Parenting MonochorionicMonozygotic

monosomy - having a single copy of a chromosome, rather than the usual pair.

 


Monosomy - A condition in which only one copy of a chromosome pair is present, instead of the normal 2. The abnormality is generally not compatible with life.

The term monosomy is used to describe the absence of one member of a pair of chromosomes. Therefore, there is a total of 45 chromosomes in each cell of the body, rather than 46.

Chromosome 4, Partial Monosomy 4p
Chromosome 4, Partial Monosomy 4q
Chromosome 4, Partial Monosomy of Distal...
Chromosome 4, Partial Trisomies 4q2 and ...
Chromosome 4, Partial Trisomy 4 (q25-qte...
Chromosome 4, Partial Trisomy 4 (q26 or ...

Monosomy X is due to the loss of a sex chromosome. Each of these is caused by an error of cell division, usually in the division that produces the unfertilized egg. Errors occur because of the physiological conditions in mother's body.

This is why the condition is also known as 'trisomy 21'. Other chromosomal abnormalities include Turner's syndrome ("monosomy X", or the presence of a single sex chromosome), Edward's syndrome ('trisomy 18') and Patau's syndrome ('trisomy 13').

abnormality such as a chromosomal imbalance, loss, or gain. Types of chromosomal abnormalities may include small chromosomal rearrangements, small duplications of chromosomal material (trisomy), or small deletion of chromosomal material (monosomy).

Fluorescence in-situ hybridization (FISH) is one technique that can be applied to identify particular chromosomes of the fetal cells recovered from maternal blood and diagnose aneuploid conditions such as the trisomies and monosomy X.

A molar pregnancy is treated by a D&C and sometimes methotrexate. Monosomy: the absence of one chromosome of a pair. Mycoplasma (T-strain mycoplasma): a microscopic organism thought to be responsible for pregnancy loss. Back to top ...

See also: Infection, Diagnosis, Chromosome, Pregnancy, Infections