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Teratogenic

Pregnancy & Parenting TENSTeratogens

A non-teratogenic agent is one which does not cause birth defects.
What are some examples of non-teratogenic agents?

 


Teratogenic: Causes abnormal development.
Thalassemia: Group of inherited disorders of hemoglobin metabolism, which results in a decrease in the amount of hemoglobin formed.

teratogenic problems
What are chromosomal abnormalities?
Chromosomal abnormalities in the baby may be inherited from the parent or may occur with no family history. The following chromosomal problems are the most common: ...

Toxic or teratogenic chemicals or biohazard substances.

HAZARDOUS SUBSTANCES AT WORK ...

Fetal hydantoin syndrome (FHS) is a well recognized teratogenic condition, the main features of which are structural heart defects, cleft lip/palate, craniofacial anomalies, distal limb hypoplasia, and developmental delay.

If adjuvant chemotherapy is necessary, it should not be given during the first trimester to avoid the risk of teratogenicity.

The FDA Pregnancy Categories are designed to measure the teratogenic effects of a drug on a growing fetus. Teratogenic means that a substance or drug is able to interfere with the development of a fetus.

Category C: Either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women, or studies in women and animals are not available.

Koren G, Levichek Z. 2002. The teratogenicity of drugs for nausea and vomiting of pregnancy: Perceived versus true risk. Am J Obstet Gynecol.186(5); 248-252.

Although animal reproductive studies have not revealed teratogenic or embryotoxic effects, nalbuphine should only be administered to pregnant women when, in the judgement of the physician, the potential benefits outweigh the possible hazards.

Teratogenicity of High Vitamin A Intake. The New England Journal of Medicine, 333(21), 1369-1373.
National Institutes of Health (NIH) Office of Dietary Supplements. (2006). Dietary Supplement Fact Sheet: Vitamin A and Carotenoids.

See also: Pregnancy, Pregnant, During pregnancy, Fetus, Prenatal