Translocation Down Syndrome
What is translocation Down syndrome?
Translocation Down syndrome refers to the type of Down syndrome that is caused by rearranged chromosome material.
Translocation. A rearrangement of a chromosome segment from one location to another, either within the same chromosome or to another.
translocation -- a chromosomal anamoly where two pieces of genetic material are switched in position.
Translocation - An error occurring during replication of chromosomes in which a chromosome, or part of it, becomes attached to another chromosome.
translocation - when the location of specific chromosome material moves to another chromosome.
trinucleotide repeats - several triplets of the DNA alphabet in a row.
trisomy - having three copies of one chromosome, rather than two copies.
Balanced Translocation (BT)
Balanced Translocation is present if a person has the correct number of chromosomes, but the pieces are joined up incorrectly. The problem can be inherited from one parent and then balanced out by the other.
Balanced Translocation (BT) -- Is when a person has the correct number of chromosomes, but the pieces are joined up incorrectly. The problem can be inherited from one parent and then balanced out by the other.
Single nucleotide polymorphism microarray-based concurrent screening of 24-chromosome aneuploidy and unbalanced translocations in preimplantation human embryos.
Fertil Steril. [Abstract] [Full-text] ...
If it proves impossible to find out that result or if he had a translocation, a blood sample from your fiancé should be obtained for chromosome analysis. The odds are obviously small that he will prove to be a carrier of the translocation.
The second type, translocation Down syndrome, occurs less frequently than trisomy 21 (only about 3 percent of the time). In this type, the extra chromosome 21, or section of it, connects itself to another chromosome.
In some cases extra material from a piece of chromosome 18 becomes attached to another chromosome (translocation).
It emerged that I have what is called a balanced translocation of chromosomes 1 and 17. A person carrying a balanced translocation shows no signs of abnormality, but these normal sets of relatively minor chromosomes get a little mixed up.
Perhaps you were told there was a translocation, deletion or ring chromosome. You will have had your own chromosomes tested. If your chromosomes are normal, you might be told that you will have no future problems.
There are also two other types of chromosomal abnormalities (mosaicism and translocation) that to a lesser extent are also implicated as possible causes of Down syndrome.
It also applies to chromosomal abnormalities such as translocation, in which one parent has a rearrangement of chromosome such that 25 percent of the embryos could be abnormal.
I got the prelims back, no downs or abnormal things so far. The final results will tell if there are any translocations of the chromosomes, so I am hoping that will be good. AND ITS A BOY!!! YEA!! What a great birthday this will be...minus the beer!! ...
Karyotyping can only determine if specific chromosomal abnormalities are present in the person tested (for instance, a balanced translocation), ...
This test is done in couples who suffer from recurrent miscarriages to look for a specific chromosomal abnormality called "translocation", which can result in the loss of important genetic material therefore causing miscarriages.
This is detected by doing a chromosomal study on the parent's blood. The commonest problem is a structural defect (break or loss of a piece of the chromosome, called a deletion; a rearrangement of a bit of a chromosome, called a translocation ) .
 See also: Pregnancy, Chromosome, Genetic, During pregnancy, Pregnant
  
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