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Pregnancy & Parenting TrisomyTrophoblastic disease

Gestational trophoblastic disease (GTD) represents a spectrum of proliferative trophoblastic abnormalities.

 


New England Trophoblastic Disease Center, Brigham and Women's Hospital, Department of Obstetrics and Gynecology, Boston, MA 02115, USA. nhorowitz@partners.org ...

Gestational Trophoblastic Disease (GTD)
About 90% of women that have a "mole" removed require no further treatment; ...

GESTATIONAL TROPHOBLASTIC DISEASE LINKS
Baby Zone - Molar Pregnancy
MyMolarPregnancy.com: Support Group, Information, Links, Personal Stories ...

Trophoblastic disease: An abnormal pregnancy in which there is no fetus, only an abnormal mass growth.
Tubal ligation: A sterilization procedure in which a woman's fallopian tubes are cut and tied off to prevent pregnancy.

Trophoblast: Cell layer important in early development of the embryo and fetus. It provides nourishment from the mother to the fetus and participates in the formation of the placenta.
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Trophoblastic disease doesn't keep most women from becoming pregnant later.3 ...

Trophoblast - The outer layer of the cells forming the wall of the blastocyst. Trophoblasts play an important role in attaching the early embryo to the uterine wall and in the eventual formation of the placenta.

Trophoblastic Disease (Molar Pregnancy)
Trophoblastic Disease - the fertilization of an egg without a nucleus. A baby (usually anomalous) may or may not be present, and the placenta develops into a nonmalignant tumor called a hydatidiform mole.

Trophoblast -- embryonal tissue that contributes to the formation of the placenta.

Gestational Trophoblastic Diseases During Pregnancy - Conditions and Treatment for GTD or Gestational trophoblastic disease during pregnancy
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Gestational Trophoblastic Disease (GTN): Abnormal pregnancy with cystic growth of the placenta; symptoms include bleeding during early and middle pregnancy

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False positive results can result from diseases like choriocarcinomas, IgA deficiencies, heterophile antibodies, enterocystoplasties, gestational trophoblastic diseases (GTD), gestational trophoblastic neoplasms (GTN), ...

Molar Pregnancy (Trophoblastic Disease) -- the fertilization of an egg without a nucleus. A baby (usually anomalous) may or may not be present, and the placenta develops into a nonmalignant tumor called a hydatidiform mole.

Trophoblastic disease: trophoblastic cells normally contribute to the formation of the placenta and are the pathway through which the baby receives nutrients from the placenta. See "molar pregnancy." Tubal pregnancy: see "ectopic pregnancy.

About 15% to 20% of complete molar pregnancies develop trophoblastic disease that keeps growing after the molar pregnancy is removed. A small percentage of these may become invasive cancer.

Beginning at about a week following conception and implantation of the developing embryo into the uterus, the trophoblast will produce enough detectable beta-HCG (the beta subunit of human chorionic gonadotropin) to diagnose pregnancy.

In a very few cases, however, persistent gestational trophoblastic disease can lead to an extremely rare form of cancer. This is called choriocarcinoma, and spreads to other organs. This can also be successfully treated with chemotherapy (ISSTD 2010).

Cell differentiation of the zygote has already begun: between the inner layer of cells or blastocyst and the outer layer or trophoblast .

Special tissues of the placenta, cells called "trophoblasts," are the cells that receive diffused and transferred substances from the mother's blood (those so-called puddles).

Hydatidiform mole/molar pregnancy - the trophoblast (which would become the placenta) becomes a mass of fluid-filled cells. There may be no embryo, or only the early signs of one.

A molar pregnancy, also called gestational trophoblastic disease, is not always a true pregnancy. If there is a fetus, there are usually abnormalities not compatible with life outside the uterus.

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2 Meekins JW, Pijnenborg R, Hanssens M, McFayden IR, van Asshe A. A study of placental bed spiral arteries and trophoblast invasion in normal and severe preeclamptic pregnancies. Br J Obstet Gynecol 1994; 101: 669-74.

It is also known as gestational trophoblastic disease (GTD). Some symptoms of molar pregnancy are vaginal bleeding, high level of HCG in blood test, absence of fetal heart tones.

A molar pregnancy is an abnormal pregnancy that affects approximately 1 our of every 1,000 pregnancies. A molar pregnancy may also be referred to as gestational trophoblastic disease, hydatidiform mole or mole.

Another name for this is gestational trophoblastic disease. The abnormal placental tissue grows and often causes enlargement of the uterus that is more rapid than usual. This condition occurs in about 1:1000 pregnancies.

Molar pregnancies are a rare cause of early bleeding. Often referred to as a "mole", a molar pregnancy involves the growth of abnormal tissue instead of an embryo. It is also referred to as gestational trophoblastic disease (GTD).

When the fertilized egg develops outside of the uterus, usually in the fallopian tube, it may cause cramping and bleeding.
Molar pregnancy. Also known as a hydatidiform mole or trophoblastic disease, ...

Too little amniotic fluid
Too much amniotic fluid ( polyhydramnios)
Tumors of pregnancy, including gestational trophoblastic disease
Other problems with the ovaries, uterus, and remaining pelvic structures ...

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See also: Pregnancy, Gestation, Uterus, Tissue, Placenta